Visual Basic (VB) is a programming language developed by Microsoft. To change the color of a control, such as a button, in response to a click event in VB, you can use the following steps: 1. Set the default color property of the control. 2. In the click event handler of the control, use the 'Color' property to set a new color. This can be done by referencing a color constant or by creating a new color object.