HSLA (Hue, Saturation, Lightness, Alpha) is a color space that represents colors as a combination of hue, saturation, lightness, and opacity. It is similar to the HSL (Hue, Saturation, Lightness) color space but adds an alpha channel to control the transparency of the color. When people say 'a nice color in HSLA', they are referring to a color that is pleasing to the eye with specific values for hue, saturation, lightness, and opacity.