WinCC (Windows Control Center) is an industrial software from Siemens for creating and managing human-machine interfaces. The 'design color change' refers to modifying the color scheme of the graphical user interface (GUI) in WinCC. This can be done by adjusting color properties in the design environment, such as selecting different themes or manually changing colors of elements. To change colors in WinCC, users typically navigate to the properties panel of the desired GUI component and modify the color settings accordingly.