A color scheme typically refers to a set of colors used in design to create a harmonious and aesthetically pleasing appearance. A 25-color scheme implies a collection of 25 distinct colors, which could be used in various design applications such as graphic design, web design, interior design, etc. Designers often select colors based on color theory principles like complementary, analogous, triadic, or monochromatic schemes. These schemes can influence the mood and atmosphere of a design.